Organism
Make a selection from the list of organisms. All queries reference miRNA genomic location data from the Sanger miRBase. Location data will be reviewed and updated quarterly.
Cluster Distance
Enter the maximum desired distance (in nucleotides) between any two adjacent miRNAs considered to be in the same cluster. For example, entering a distance of 1000 would produce a list of all non-singleton clusters of miRNAs in the selected genome such that no two adjacent miRNAs in a cluster are more than 1 Kilobase apart.
Link to
This menu selection determines the type of links generated for each cluster when the "Find Clusters" button is pressed. Link availability varies according to Organism. Selections include:
- UCSC View links to a UCSC browser view of each cluster.
- Experimentally Supported Targets links to targets contained in DIANA Tarbase.
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Predicted Targets: Union, Intersection, and Individual Programs
Please see the Targets Help section for a description of predicted target sets.
Advanced Query Options
- There is some evidence that miRNAs located within protein-coding genes may be processed from the mRNAs of these "host genes". We provide the option to considered all miRNAs located within the same gene as a cluster (co-transcribed unit).
- Additionally, if a protein-coding gene intervenes between two miRNAs on the genome, the user may wish infer that these two miRNAs are not transcribed together. We provide the option to enforce cluster breaks in the case of an intervening gene.